Beauty Bus was founded in memory of Melissa Marantz Nealy, whose life was cut short at the young age of 28 by a degenerative neuromuscular disease. Melissa became homebound as her disease progressed. In an effort to lift her spirits, her family arranged for in-home haircuts, manicures, and facials. Melissa said these treatments made her feel "human again."

The impact on Melissa's emotional well-being was profound. She felt nurtured by the beauty professionals who provided a momentary escape from her disease. Melissa family founded Beauty Bus Foundation in 2009 to offer this same experience of dignity, hope, and respite to other families when they need it most.